ISAⁱ is an acronym for Instruction Set Architecture. This term is used to refer to all of the instructions supported by a particular microprocessor. For instance, most general desktop computers use Intel 386+ microprocessors which use the 386 ISAⁱ.

The EECS 388 course at the University of Kansas makes use of the MicroBlazeⁱ soft-processorⁱ which defines and uses the MicroBlazeⁱ ISAⁱ. The MicroBlazeⁱ is based on the DLXⁱ architecture and, thus, has an ISAⁱ which is very similar to the DLXⁱ ISAⁱ.

In the EECS 443 course at the University of Kansas students design and implement a custom microprocessor which uses the KURM ISAⁱ. This ISAⁱ is a simple, 16-bit integer architecture designed by instructors for understandability and ease of implementation.